Pulsatilla alba: analytical review of spread, chemical composition, biological activity and medical application

Authors

DOI:

https://doi.org/10.15587/2519-8025.2021.249850

Keywords:

Pulsatilla alba, biologically active plants, endangered species, in vitro reproduction, pharmacological activity

Abstract

The object of analytical study is the medicinal plant Pulsatilla alba. This species is rare, the stocks of herbal raw materials are limited, and there are no Pulsatilla alba-based medicines on the Ukrainian market.

The aim of study was to analyze and summarize data on the range, content of biologically active compounds and the spectrum of use in pharmacy and medicine Pulsatilla alba.

Materials and methods. Literary and electronic sources of information on the distribution, chemical composition and pharmacological activity of Pulsatilla alba.

Results. Pulsatilla alba is a plant of the Ranunculaceae family, characterized by a high content of biologically active organic compounds, namely organic acids, traces of alkaloids, vitamins, resinous and tannins, about 20 different macro-and micronutrients, essential oils, γ-lactones, triterpenoids, sterols, chelidonic acid, coumarins, as well as giving it protection status make it an interesting object for research.

Analysis of scientific publications revealed that plants of the family Ranunculaceae, in particular, Pulsatilla alba contain a significant amount of biologically active substances, have numerous pharmacological activities, have long been used in folk medicine, and is a promising raw material for the production of phytopreparations. The volume of processing of medicinal plant raw materials in Ukraine in one year is from 5 to 6 thousand tons, the amount of raw materials for export reaches more than 3 thousand tons per year. About 1,000 tons of raw materials consumed in Ukraine are imported and 1,500 tons are domestically produced.

Conclusions. Therefore, as populations of rare low-competitive species of the Ranunculaceae family are particularly endangered, displaced by tree, shrub and highly competitive trivial violent herbaceous species due to the widespread use of Pulsatilla alba in folk medicine as an antitumor, hypnotic, hypnotic, antifungal, antifungal research which should be continued

Author Biographies

Anna Krvavych, Lviv Polytechnic National University

PhD, Senior lecturer

Department of Technology of Biologically Active Substances, Pharmacy and Biotechnology

Nataliia Reviakina, Lviv Polytechnic National University

Department of Technology of Biologically Active Substances, Pharmacy and Biotechnology

Lesia Zhurakhivska, Lviv Polytechnic National University

PhD, Associate Professor

Department of Technology of Biologically Active Substances, Pharmacy and Biotechnology

Iryna Hubytska, Lviv Polytechnic National University

PhD, Associate Professor

Department of Technology of Biologically Active Substances, Pharmacy and Biotechnology

Roksolana Konechna, Lviv Polytechnic National University

PhD, Associate Professor

Department of Technology of Biologically Active Substances, Pharmacy and Biotechnology

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Published

2021-12-30

How to Cite

Krvavych, A., Reviakina, N., Zhurakhivska, L., Hubytska, I., & Konechna, R. (2021). Pulsatilla alba: analytical review of spread, chemical composition, biological activity and medical application. ScienceRise: Biological Science, (4 (29), 10–14. https://doi.org/10.15587/2519-8025.2021.249850

Issue

No. 4 (29) (2021)

Section

Biological research

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Copyright (c) 2021 Anna Krvavych, Nataliia Reviakina, Lesia Zhurakhyvska, Iryna Hubytska, Roksolana Konechna

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