The malondialdehyde level in the culture cells under the influence of compounds with stimulating and inhibitory effects on proliferation

Authors

  • Дмитро Васильович Шелест NSC "Institute of Biology and Medicine" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601, Ukraine
  • Ольга Вікторівна Колотій NSC "Institute of Biology and Medicine" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601, Ukraine
  • Катерина Олексіївна Свиридова NSC "Institute of Biology and Medicine" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601, Ukraine
  • Людмила Василівна Гарманчук NSC "Institute of Biology and Medicine" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601, Ukraine https://orcid.org/0000-0002-5805-1930

DOI:

https://doi.org/10.15587/2519-8025.2016.83401

Keywords:

malondialdehyde, lipid peroxidation, TBA-active products, diene conjugates

Abstract

The optimal method for the determination of lipid peroxidation product - malondialdehyde (MDA) in cell culture was selected and the effect of test drugs on the level of TBA-active products of MAEC, HeLa and L1210 cells was determined. The MDA level in MAEC cells is different from control by 2.7 times, for HeLa – by 3.6 times, and for L1210- by 4 times

Author Biographies

Дмитро Васильович Шелест, NSC "Institute of Biology and Medicine" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601

Postgraduate student

Department of Biochemistry

Ольга Вікторівна Колотій, NSC "Institute of Biology and Medicine" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601

Department of Biochemistry

Катерина Олексіївна Свиридова, NSC "Institute of Biology and Medicine" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601

Department of Biochemistry

Людмила Василівна Гарманчук, NSC "Institute of Biology and Medicine" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601

Doctor of Biological Sciences, Professor

Department of Basic Medicine

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Published

2016-11-18

How to Cite

Шелест, Д. В., Колотій, О. В., Свиридова, К. О., & Гарманчук, Л. В. (2016). The malondialdehyde level in the culture cells under the influence of compounds with stimulating and inhibitory effects on proliferation. ScienceRise: Biological Science, (3 (3), 61–64. https://doi.org/10.15587/2519-8025.2016.83401

Issue

No. 3 (3) (2016)

Section

Biological Sciences

License

Copyright (c) 2016 Дмитро Васильович Шелест, Ольга Вікторівна Колотій, Катерина Олексіївна Свиридова, Людмила Василівна Гарманчук

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