Risk factors and prevention of postmastectomic syndrome in breast cancer surgery

Authors

  • Yuriy Vinnyk Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkiv, Ukraine, 61176, Ukraine
  • Vadim Vlasenko Molecule Medical Center Gogolia str., 7, Kharkiv, Ukraine, 61057, Ukraine https://orcid.org/0000-0002-8215-1958
  • Anna Baranova Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkiv, Ukraine, 61176 State Institution « S. P. Grigoriev Institute of Medical Radiology of National Academy of Medical Sciences of Ukraine » Pushkinska str., 82, Kharkiv, Ukraine, 61024, Ukraine https://orcid.org/0000-0002-2419-9910

DOI:

https://doi.org/10.15587/2519-4798.2020.193288

Keywords:

breast cancer, radical surgery, postoperative edema, postmastectomy syndrome, risk factors, prevention

Abstract

Postmastectomy syndrome (PMES) is considered one of the most frequent complications after radical operations in patients with breast cancer (BC).

The aim of the study was to identify risk factors and develop preventive measures for PMES after radical operations in BC patients.

Materials and methods. The immediate results of surgical treatment of 147 women with BC who underwent radical surgery were analyzed: the frequency of postoperative edema and PMES depending on the initial clinical and pathological parameters and treatment features using descriptive statistics, χ2 criterion, and correlation analysis.

Results. PMES during the observation period was diagnosed in 17 (11.6 %) patients, including: I st. – in 7 (4.8 %); II st. – in 9 (6.1 %) and III st. in one case (0.7 %). In most cases, its development was associated with postoperative edema, which was detected in the early postoperative period in 15 (88 %) of these patients. The dependence of the incidence of PMES on BMI and the age of patients with a tendency to increase it with the use of adjuvant radiation therapy and decrease with primary breast plastic surgery has been established. The use of a complex of preventive measures led to a decrease in the frequency of PMES (from 17 % to 2 %).

Conclusions. In patients with BC, a frequent complication of radical surgery is postoperative edema of the upper limb and / or PMES, the risk of which increases with increasing age and BMI, as well as with the use of adjuvant radiation therapy. The use of a complex of preventive measures helps to significantly reduce the frequency of these complications

Author Biographies

Yuriy Vinnyk, Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkiv, Ukraine, 61176

MD, Professor

Department of Oncological Surgery, Radiation Therapy and Palliative Care

Vadim Vlasenko, Molecule Medical Center Gogolia str., 7, Kharkiv, Ukraine, 61057

PhD

Anna Baranova, Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkiv, Ukraine, 61176 State Institution « S. P. Grigoriev Institute of Medical Radiology of National Academy of Medical Sciences of Ukraine » Pushkinska str., 82, Kharkiv, Ukraine, 61024

Postgraduate Student

Department of Oncological Surgery, Radiation Therapy and Palliative Care

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Published

2020-01-30

How to Cite

Vinnyk, Y., Vlasenko, V., & Baranova, A. (2020). Risk factors and prevention of postmastectomic syndrome in breast cancer surgery. ScienceRise: Medical Science, (1 (34), 46–50. https://doi.org/10.15587/2519-4798.2020.193288

Issue

No. 1 (34) (2020)

Section

Medical Science

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Copyright (c) 2020 Yuriy Vinnyk, Vadim Vlasenko, Anna Baranova

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