Optimization of the isolation of biologically active complexes from buds and shoots of birch and poplar buds for their further use in cosmeceutical compositions

Authors

DOI:

https://doi.org/10.15587/2519-4852.2023.273394

Keywords:

Birch, poplar, essential oils, biologically active complexes, extraction, barothermal method, hydrodistillation, cosmeceuticals

Abstract

The aim is to optimize the isolation of biologically active birch and poplar complexes based on woodworking industry waste to study their biological activity to create cosmeceutical compositions that have cosmetic and pharmaceutical effects.

Materials and methods. The object of research is the vegetative organs of birch (buds and shoots) and poplar (buds). In the process of work, experimental studies were carried out on the extraction and separation of natural compounds, development of biological complexes of vegetative organs of birch and poplar, study of the chemical composition and standardization of biologically active complexes of birch and preparations based on them.

Results. The optimal methods for extracting natural complexes were determined. Created as a semi-industrial installation for producing biologically active complexes by barothermal method, combining two processes - high pressure and hydrodistillation. The optimal operating cycle and plant parameters were determined. The optimal solvents for the extraction of biologically active complexes from the vegetative organs of birch and poplar have been determined. Petroleum ether (33.60 %) extracted the most compounds from birch buds, in birch shoots - ethanol (8.34 %). Qualitative and quantitative indicators of biologically active complexes are determined, and projects for examining the obtained biologically active complexes are proposed. We determined the yield of essential oil depending on the time of collection of raw materials and determined that the largest amount of essential oil is contained in spring buds (0.21 % of dry raw materials) and shoots (0.08 %).

Conclusions. Biological complexes created from timber processing waste with high activity are the basis for the creation of cosmetic products. The created semi-industrial plant will provide the basis for creating new original products in industrial volumes.

Author Biographies

Alyona Yanevich, M. Kozybayev North Kazakhstan University

Master

Department of Chemistry and Chemical Technology

Dmitriy Mokshin , M. Kozybayev North Kazakhstan University

Master, PhD student

Department of Chemistry and Chemical Technology

Vladilen Polyakov, M. Kozybayev North Kazakhstan University

Doctor of Chemical Sciences, Professor

Department of Chemistry and Chemical Technology

References

  1. Distribution of forested land by dominant forest species and groups (2020). State accounting of the forest fund of the North Kazakhstan region.
  2. Lezhneva, M. Yu. (2006). Terpene compounds of birch, their chemical modifications and biological activity. Astana: Institute of Phytochemistry, 24.
  3. Chen, S., Zhao, X., Chen, S. (2022). Identification of the cell wall synthesis genes in betula pendula. Wood Research, 67 (4), 519–532. doi: https://doi.org/10.37763/wr.1336-4561/67.4.519532
  4. Hynynen, J., Niemisto, P., Vihera-Aarnio, A., Brunner, A., Hein, S., Velling, P. (2009). Silviculture of birch (Betula pendula Roth and Betula pubescens Ehrh.) in northern Europe. Forestry, 83 (1), 103–119. doi: https://doi.org/10.1093/forestry/cpp035
  5. Harr, L., Esper, J., Kirchhefer, J. A., Zhou, W., Hartl, C. (2020). Growth response of Betula pubescens Ehrh. to varying disturbance factors in northern Norway. Trees, 35 (2), 421–431. doi: https://doi.org/10.1007/s00468-020-02043-1
  6. Havlik, J., de la Huebra, R. G., Hejtmankova, K., Fernandez, J., Simonova, J., Melich, M., Rada, V. (2010). Xanthine oxidase inhibitory properties of Czech medicinal plants. Journal of Ethnopharmacology, 132 (2), 461–465. doi: https://doi.org/10.1016/j.jep.2010.08.044
  7. Gründemann, C., Gruber, C. W., Hertrampf, A., Zehl, M., Kopp, B., Huber, R. (2011). An aqueous birch leaf extract of Betula pendula inhibits the growth and cell division of inflammatory lymphocytes. Journal of Ethnopharmacology, 136 (3), 444–451. doi: https://doi.org/10.1016/j.jep.2011.05.018
  8. Bljajić, K., Šoštarić, N., Petlevski, R., Vujić, L., Brajković, A., Fumić, B. et al. (2016). Effect ofBetula pendulaLeaf Extract onα-Glucosidase and Glutathione Level in Glucose-Induced Oxidative Stress. Evidence-Based Complementary and Alternative Medicine, 2016, 1–8. doi: https://doi.org/10.1155/2016/8429398
  9. Rastogi, S., Pandey, M. M., Kumar Singh Rawat, A. (2015). Medicinal plants of the genus Betula – Traditional uses and a phytochemical–pharmacological review. Journal of Ethnopharmacology, 159, 62–83. doi: https://doi.org/10.1016/j.jep.2014.11.010
  10. Svanberg, I., Sõukand, R., Łuczaj, Ł., Kalle, R., Zyryanova, O., Dénes, A. et al. (2012). Uses of tree saps in northern and eastern parts of Europe. Acta Societatis Botanicorum Poloniae, 81 (4), 343–357. doi: https://doi.org/10.5586/asbp.2012.036
  11. Eddouks, M., Maghrani, M., Lemhadri, A., Ouahidi, M.-L., Jouad, H. (2002). Ethnopharmacological survey of medicinal plants used for the treatment of diabetes mellitus, hypertension and cardiac diseases in the south-east region of Morocco (Tafilalet). Journal of Ethnopharmacology, 82 (2-3), 97–103. doi: https://doi.org/10.1016/s0378-8741(02)00164-2
  12. Blanco, E., Macı́a, M. J., Morales, R. (1999). Medicinal and veterinary plants of El Caurel (Galicia, northwest Spain). Journal of Ethnopharmacology, 65 (2), 113–124. doi: https://doi.org/10.1016/s0378-8741(98)00178-0
  13. Neves, J. M., Matos, C., Moutinho, C., Queiroz, G., Gomes, L. R. (2009). Ethnopharmacological notes about ancient uses of medicinal plants in Trás-os-Montes (northern of Portugal). Journal of Ethnopharmacology, 124 (2), 270–283. doi: https://doi.org/10.1016/j.jep.2009.04.041
  14. Miraldi, E., Ferri, S., Mostaghimi, V. (2001). Botanical drugs and preparations in the traditional medicine of West Azerbaijan (Iran). Journal of Ethnopharmacology, 75 (2-3), 77–87. doi: https://doi.org/10.1016/s0378-8741(00)00381-0
  15. Bélanger, A., Grenier, A., Simard, F., Gendreau, I., Pichette, A., Legault, J., Pouliot, R. (2019). Dihydrochalcone Derivatives from Populus balsamifera L. Buds for the Treatment of Psoriasis. International Journal of Molecular Sciences, 21 (1), 256. doi: https://doi.org/10.3390/ijms21010256
  16. Dudonné, S., Poupard, P., Coutière, P., Woillez, M., Richard, T., Mérillon, J.-M., Vitrac, X. (2011). Phenolic Composition and Antioxidant Properties of Poplar Bud (Populus nigra) Extract: Individual Antioxidant Contribution of Phenolics and Transcriptional Effect on Skin Aging. Journal of Agricultural and Food Chemistry, 59 (9), 4527–4536. doi: https://doi.org/10.1021/jf104791t
  17. Pobłocka-Olech, L., Inkielewicz-Stepniak, I., Krauze-Baranowska, M. (2019). Anti-inflammatory and antioxidative effects of the buds from different species of Populus in human gingival fibroblast cells: Role of bioflavanones. Phytomedicine, 56, 1–9. doi: https://doi.org/10.1016/j.phymed.2018.08.015
  18. Zhang, C., Zheng, H., Liu, G., Hu, F. (2011). Development and validation of HPLC method for determination of salicin in poplar buds: Application for screening of counterfeit propolis. Food Chemistry, 127 (1), 345–350. doi: https://doi.org/10.1016/j.foodchem.2011.01.014
  19. Castaldo, S., Capasso, F. (2002). Propolis, an old remedy used in modern medicine. Fitoterapia, 73, S1–S6. doi: https://doi.org/10.1016/s0367-326x(02)00185-5
  20. Darra, E., Abdel-Azeim, S., Manara, A., Shoji, K., Maréchal, J.-D., Mariotto, S. et al. (2008). Insight into the apoptosis-inducing action of α-bisabolol towards malignant tumor cells: Involvement of lipid rafts and Bid. Archives of Biochemistry and Biophysics, 476 (2), 113–123. doi: https://doi.org/10.1016/j.abb.2008.02.004
  21. Piochon-Gauthier, M., Legault, J., Sylvestre, M., Pichette, A. (2014). The Essential Oil of Populus balsamifera Buds: Its Chemical Composition and Cytotoxic Activity. Natural Product Communications, 9 (2), 257–260. doi: https://doi.org/10.1177/1934578x1400900231
  22. Kuś, P. M., Okińczyc, P., Jakovljević, M., Jokić, S., Jerković, I. (2018). Development of supercritical CO2 extraction of bioactive phytochemicals from black poplar (Populus nigra L.) buds followed by GC–MS and UHPLC-DAD-QqTOF-MS. Journal of Pharmaceutical and Biomedical Analysis, 158, 15–27. doi: https://doi.org/10.1016/j.jpba.2018.05.041
  23. Simard, F., Legault, J., Lavoie, S., Pichette, A. (2014). Balsacones D-I, dihydrocinnamoyl flavans from Populus balsamifera buds. Phytochemistry, 100, 141–149. doi: https://doi.org/10.1016/j.phytochem.2013.12.018
  24. Kabishev, K. E., Sakanyan, E. I. (2002). Determination of extractive substances in medicinal plant raw materials with various technologies for obtaining extracts. Plant Resources, 38 (3), 113.
  25. Nadirov, R. S., Polyakov, V. V., Adekenov, S. M. (2002). Pre-Pat. No. 11387 KZ. Barotermicheskiy sposob polucheniya masla topolya bal'zamicheskogo. MKP A61K 35/78. published: 15.04.2002, Bul. No. 4
  26. Park, K. J., Subedi, L., Kim, S. Y., Choi, S. U., Lee, K. R. (2018). Bioactive triterpenoids from twigs of Betula schmidtii. Bioorganic Chemistry, 77, 527–533. doi: https://doi.org/10.1016/j.bioorg.2018.02.006
  27. Adekenov, S. M., Baysarov, G. M., Khabarov, I. A., Polyakov, V. V. (2020). Flavonoids of populus Balsamifera L. buds and methods for their isolation. Chemistry of Plant Raw Material, 2, 181–188. doi: https://doi.org/10.14258/jcprm.2020027602

Downloads

Published

2023-02-28

How to Cite

Yanevich, A., Mokshin , D., & Polyakov, V. . (2023). Optimization of the isolation of biologically active complexes from buds and shoots of birch and poplar buds for their further use in cosmeceutical compositions. ScienceRise: Pharmaceutical Science, (1(41), 67–76. https://doi.org/10.15587/2519-4852.2023.273394

Issue

No. 1(41) (2023)

Section

Pharmaceutical Science

License

Copyright (c) 2023 Alyona Yanevich, Dmitriy Mokshin , Vladilen Polyakov

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Our journal abides by the Creative Commons CC BY copyright rights and permissions for open access journals.