Study of the component composition of essential oils of pentaphylloides Fruticosa (L.) О. Schwarz (Dasiphora fruticosa (L.) Rybd.) raw materials

Tetiana Kostashchuk; Andriy Grytsyk; Lyubov Grytsyk; Thanh Tung Nguyen; Ain Raal; Oleh Koshovyi

doi:10.15587/2519-4852.2025.326765

Authors

Tetiana Kostashchuk Ivano-Frankivsk National Medical University, Ukraine https://orcid.org/0000-0002-2495-4509
Andriy Grytsyk Ivano-Frankivsk National Medical University, Ukraine https://orcid.org/0000-0001-7335-887X
Lyubov Grytsyk Ivano-Frankivsk National Medical University, Ukraine https://orcid.org/0000-0003-0338-1462
Thanh Tung Nguyen Hanoi University of Pharmacy, Estonia https://orcid.org/0000-0002-5740-7392
Ain Raal University of Tartu, Estonia https://orcid.org/0000-0001-8731-7366
Oleh Koshovyi National University of Pharmacy; University of Tartu, Ukraine https://orcid.org/0000-0001-9545-8548

DOI:

https://doi.org/10.15587/2519-4852.2025.326765

Keywords:

Pentaphylloides fruticosa (L.) О. Schwarz, Dasiphora fruticosa (L.) Rybd., essential oil, medicinal plant raw materials, shoots, gas chromatography-mass spectrometry

Abstract

Pentaphylloides fruticosa (L.) О. Schwarz (Dasiphora fruticosa (L.) Rybd.) is one of the most common species in Eurasia. There are about 150 known varieties of Pentaphylloides fruticosa, which are used as an ornamental plant. The content of tannins, polyphenols, flavonoids, and macro- and microelements was detected and determined in the above-ground part of some varieties of Pentaphylloides fruticosa. Studies on the content and composition of essential oils have not been conducted.

The aim. The aim of the work was to study the quantitative composition and identification of components of essential oil from raw materials Pentaphylloides fruticosa.

Materials and methods. Hydrodistillates obtained from dried raw materials of Pentaphylloides fruticosa, collected from different growing sites in Ivano-Frankivsk and Vinnytsia regions (Ukraine), were analyzed by gas chromatography-mass spectrometry.

Research results. Up to 91 essential oil components were identified and quantified in the studied raw materials. The content of essential oils was from 0.52 to 3.11 mL/kg, depending on the type of raw material. The predominant essential oil compounds in the raw material of Pentaphylloides fruticosa were linalool, geraniol, (E)-β-damascenone, (E)-geranylacetone, (E)-β-ionone, L-β-elemene, germacrene D, hexahydrofarnesyl acetone, phytol, benzyl benzoate. The largest amount of essential oil components was found in shoots with yellow flowers of Pentaphylloides fruticosa. The results of the study revealed strong positive correlation links (> 0.9) between such pairs of compounds as L-carvone and hexahydrofarnesyl acetone, benzyl benzoate and 1,2-diphenoxyethane; L-β-pinene and α-muurolene, L-β-pinene and hexahydrofarnesyl acetone; L-bornyl acetate and L-β-elemene, L-bornyl acetate and benzyl benzoate, L-bornyl and 1,2-diphenoxyethane, D-limonene and eucalyptol, L-β-pinene and L-carvone.

Conclusions. In connection with the obtained research results and the identification of such compounds as linalool, geraniol, (E)-β-damascenone, (E)-geranylacetone, (E)-β-ionone, germacrene D, phytol, benzyl benzoate, it is advisable to further study the species Pentaphylloides fruticosa, its pharmacological activity and possibilities for further application in medicine

Supporting Agency

European Union in the MSCA4Ukraine project “Design and development of 3D-printed medicines for bioactive materials of Ukrainian and Estonian medicinal plants origin” [ID number 1232466].

Author Biographies

Tetiana Kostashchuk, Ivano-Frankivsk National Medical University

Assistant

Department of Pharmaceutical Management, Drug Technology and Pharmacognosy

Andriy Grytsyk, Ivano-Frankivsk National Medical University

Doctor of Pharmaceutical Sciences, Professor, Head of Department

Department of Pharmaceutical Management, Drug Technology and Pharmacognosy

Lyubov Grytsyk, Ivano-Frankivsk National Medical University

PhD, Associate Professor

Department of Chemistry, Pharmaceutical Analysis and Postgraduate Education

Thanh Tung Nguyen, Hanoi University of Pharmacy

PhD, Lecturer

Department of Pharmacognosy

Ain Raal, University of Tartu

PhD, Professor

Institute of Pharmacy

Oleh Koshovyi, National University of Pharmacy; University of Tartu

Doctor of Pharmaceutical Sciences, Professor

Department of Pharmacognosy

Institute of Pharmacy

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