The study of amino acid composition of Persei species of Desmodium canadense herb

Authors

  • Денис Олегович Мезенцев National University of Pharmacy Pushkinska str., 53, Kharkiv, Ukraine, 61002, Ukraine https://orcid.org/0000-0003-1655-1555
  • Вікторія Сергіївна Кисличенко National University of Pharmacy Pushkinska str., 53, Kharkiv, Ukraine, 61002, Ukraine https://orcid.org/0000-0002-0684-1746
  • Надія Євгеніївна Бурда National University of Pharmacy Pushkinska str., 53, Kharkiv, Ukraine, 61002, Ukraine https://orcid.org/0000-0002-7435-5731
  • Яна Володимирівна Дьяконова Medical University of Warsaw Żwirki i Wigury str., 61, Warsaw, Poland, 02-091, Ukraine

DOI:

https://doi.org/10.15587/2519-4852.2016.80477

Keywords:

Desmodium canadense, Persei species, herb, free and bound amino acids, high performance liquid chromatography

Abstract

Persei species of Desmodium canadense is cultivated in Ukraine, and since 2012 it has been included into the State Register of plant varieties suitable for dissemination in Ukraine. The given herb has a pronounced anti-viral activity. Since nitrogen-containing compounds, amino acids particularly, participate in formation of the given type of activity, the study of this class of compounds in the mentioned herb is reasonable.

The aim of our research was to analyze amino acid composition of Persei species of Desmodium canadense herb.

Methods. HPLC method was used for the analysis of amino acid composition in the studied herbal material.

Results. In result of research, 22 amino acids and 18 free amino acids were determined in the studied object. The content of the sum of free and bound amino acids in Persei species of Desmodium canadense herb was 5.92%. Asparaginic acid was found in the given herb in the highest concentration.

Conclusion. Obtained results of research deepen the information about chemical composition of Persei species of Desmodium canadense herb and can be used for development of the phytotherapeuttic remedy on its basis

Author Biographies

Денис Олегович Мезенцев, National University of Pharmacy Pushkinska str., 53, Kharkiv, Ukraine, 61002

Department of Chemistry of Natural Compounds 

Вікторія Сергіївна Кисличенко, National University of Pharmacy Pushkinska str., 53, Kharkiv, Ukraine, 61002

Doctor of pharmaceutical sciences, professor, Head of Department

Department of Chemistry of Natural Compounds 

Надія Євгеніївна Бурда, National University of Pharmacy Pushkinska str., 53, Kharkiv, Ukraine, 61002

PhD, associate professor

Department of Chemistry of Natural Compounds 

Яна Володимирівна Дьяконова, Medical University of Warsaw Żwirki i Wigury str., 61, Warsaw, Poland, 02-091

Doctor habilitat

Department of Physical Chemistry

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Published

2016-10-30

How to Cite

Мезенцев, Д. О., Кисличенко, В. С., Бурда, Н. Є., & Дьяконова, Я. В. (2016). The study of amino acid composition of Persei species of Desmodium canadense herb. ScienceRise: Pharmaceutical Science, (3 (3), 13–15. https://doi.org/10.15587/2519-4852.2016.80477

Issue

No. 3 (3) (2016)

Section

Pharmaceutical Science

License

Copyright (c) 2016 Денис Олегович Мезенцев, Вікторія Сергіївна Кисличенко, Надія Євгеніївна Бурда, Яна Володимирівна Дьяконова

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