The study of the anti-influenza activity of Altabor substance

Authors

  • S Rybalko Institute of Epidemiology and Infectious Diseases at the Academy of Medical Science of Ukraine, Kyiv,
  • T Кrutskykh National University of Pharmacy, Kharkiv,
  • A Shalamay JSC SIC "Borshchahivka CPP", Kyiv,

Keywords:

altabor, antiviral activity, influenza.

Abstract

The antiviral activity of Altabor substance has been studied in the experiments in vitro and in ovo. The substance of Altabor actively inhibits the influenza virus reproduction in the doses from 100 μg /ml to 6,75 μg/ml by 7,5-3,0 lg of ID50, drug in the dose of 100 μg/embryo inhibits the replication of the influenza virus by 5,5 lg of EID50, and it confirms the presence of the antiviral activity of the drug.

References

Genetic analysis of influenza A virus "pandemic" H1N1 under the conditions of epidemics [Text] / Ye.S. Kostyukova, N.B. Zakharzhevskaya, P.A. Kostin et al. // Therapeutic archive. - 2012. - № 3. – Р. 48-54.

Hrynevych O.Y. Review of the epidemiological situation in the world regarding the incidence of seasonal and avian influenza in early 2012 [Text] / O.Y. Hrynevych, I.G. Markovic // Family Medicine. - 2012. - № 1. - P. 32-34.

Markovic I.G. Analysis of flue morbidity of the population of Ukraine in 2009-2013 [Text] / I.G. Markovic, O.Y. Hrynevych // Ukraine. Health of the Nation. - 2013. - № 2. - P. 118-124.

Dibrova V.A. Aspects of the pathogenesis of influenza A (H1N1) [Text] / V.A. Dibrova, Ye .V. Tsema // Modern infection. - 2010. - № 2. - P. 12-21.

Moskaliuk V. D. Dynamics of cellular immunity of acute respiratory viral infections of patients against the aerosol interferon treatment background [Text] / V. D. Moskaliuk, V. D. Sorokhan // Infectious diseases. — 2010. — № 4. — Р. 14-18.

Obertynska O.V. Modern etiotropic therapy of influenza with neuraminidase inhibitors [Text] / O.V. Obertynska // Family Medicine. - 2014. - № 1. - P. 111-114.

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How to Cite

Rybalko, S., Кrutskykh T., & Shalamay, A. (2020). The study of the anti-influenza activity of Altabor substance. Annals of Mechnikov’s Institute, (2), 131–133. Retrieved from https://journals.uran.ua/ami/article/view/192934

Issue

Section

Research Articles