The modern view of the etiology and treatment of pelvic pain in young women with genitals inflammation

Abstract

Sensitive issue of modern gynecology can be considered widespread and substantial "rejuvenation" of inflammatory diseases of the pelvic organs in women of reproductive age.Ascending path of infection prevails in the pathogenesis of inflammatory diseases of the internal genital organs. Invasion of microbes in the internal genital organs may occur during the various manipulations, different pelvic operations and  in the postpartum period. The degree of colonization of microorganisms of the vagina and cervix plays an important   role  in the development of the infectious process. In obstetrics and gynecology inflammatory diseases can be caused by pathogenic and non- pathogenic (opportunistic) microorganisms. Among the pathogens causing the defeat of the female genital organs, most often found N. gonorrhea, C. trachomatis, T. vaginalis. Opportunistic pathogens, part of the normal flora of the genital tract, in certain circumstances, can become agents of post-partum, post-abortion, post-operative complications and inflammatory diseases of the female genital organs. Among the opportunistic pathogens that are part of the normal microflora of the female genital organs, found hemolytic and non-hemolytic streptococci (the most important are streptococci groups A, B, D), coagulase-negative staphylococci and micrococci (allocated 60% and 35% of healthy women, respectively). They can cause secondary infectious processes of the urinary system, inflammatory diseases of the genital organs of pregnant women and mothers with immunosuppression. These microorganisms are often the agents of inflammatory diseases in the newborn, especially with low weight and malnutrition children. Gram-negative opportunistic bacteria that are isolated from the genital tract, can also be agents of inflammatory processes of various localization. Escherichia coli is the most frequently obtain and cause urinary tract infection in pregnant and postpartum women. It is also causative agent of postpartum sepsis and postoperative peritonitis. Among other gram-negative bacteria should be noted genus Klebsiella. Therefore, therapy of inflammatory diseases of the pelvic organs high demands due to the risk that represents this state to the reproductive function of patients. The mixed nature of the infection, the increasing rates of resistance of pathogens to antibiotics creates difficulties in selecting antimicrobial therapy, which remains the empirical  till now. The inclusion of specific bacteriophages and plant antiseptics in therapeutic regimens for local treatment of inflammatory diseases of the vagina associated with an excessive colonization of the vaginal mucosa by aerobic opportunistic bacteria justified and can serve as an alternative to the traditional antibiotic therapy.  All this determines the necessity for further studying   the etiology and pathogenesis of infectious and inflammatory complications, the development of new highly effective methods of prevention and treatment.