The impact of long COVID on the quality of life of patients living in the frontline city during hostilities
DOI:
https://doi.org/10.5281/zenodo.14275325Keywords:
long COVID, quality of life, internally displaced persons, hostilitiesAbstract
The aim of this study was to assess the quality of life (QoL) of patients with long COVID living in the frontline city Kharkiv during hostilities between Russia and Ukraine. Materials and Methods: Three groups of patients were formed using the «case-control» design. Group 1 - patients with long COVID living in Kharkiv (n = 18). Group 2 - patients who recovered from COVID and live in Kharkiv (n = 36). Group 3 - internally displaced persons (IDPs), n = 36. Pairs were matched based on criteria such as age, gender, comorbid conditions, and concomitant medication. The WHOQOL-bref questionnaire in Ukrainian was used to assess QoL. Results: QoL in Group 1 was 2,5 ± 0,73 compared to 3,1 ± 0.94 in Group 2 (p = 0,021) and 2,2 ± 0,69 in Group 3 (p 1-3 = 0,145, p 2-3 < 0,0001). The health status (HS) was the worst in Group 1 – 2,2 ± 0,71 vs 3,4 ± 0,99 in Group 2 (p 1-2 < 0,0001) and 2,8 ± 0,83 in Group 3 (p 1-3 = 0,011, p 2-3 = 0,068). Physical health was also worst in Group 1 – 34,42 ± 1,.60 vs 56,48 ± 18,31 in Group 2 (p < 0.000...) and in Group 3 – 46,28 ± 16,73 (p 1-3 = 0,01, p 2-3 = 0,02). Psychological domain did not differ significantly between Groups 1 and 2 – 51,29 ± 17,38 vs 69,27 ± 22,86 (p = 0.65), but was lower in Group 3 – 39,72 ± 13,71 (p 1-3 = 0,01, p 2-3 < 0,0001). Social relationships were rated lower by patients in Group 3 – 49,51 ± 15,44 compared to patients in Group 1 – 59,12 ± 17,89 (p = 0,046) and Group 2 – 63,19 ± 21,35 (p = 0,0027). Environment domain was lowest in Group 3 – 52,09 ± 16.32, although it did not differ significantly fro Group 1 – 57,63 ± 18,21 (p = 0,65), unlike Group 2 – 69,27 ± 22,86 (p = 0,0005). Conclusions: Patients with long COVID had a lower QoL compared to recovered patients, which was comparable to that of IDPs. Health status in these patients was the worst compared to both recovered patients and IDPs. Physical health was worst in the group of patients with long COVID, while psychological domain was poorest in the IDPs group, which also had the lowest social relationship domain. Environmental domain was equally low in both groups of patients with long COVID and IDPs.
Keywords: long COVID, quality of life, internally displaced persons, hostilities.
References
Carlile O., Briggs A., Henderson A. et al. Impact of long COVID on health-related quality-of-life: an OpenSAFELY population cohort study using patient-reported outcome measures (OpenPROMPT). The Lancet Regional Health Europe. 2024, Vol.40. P.1-15. URL:https://www.thelancet.com/journal/lanepe/article/PIIS2666-7762(24)00074-7/fulltext
Yalçın-Çolak N., Kader C., Eren-Gök S. et al. Long-term Symptoms and Quality of Life in Persons with COVID-19. Infect Dis Clin Microbiol 2023; 5(3). P.212-20 URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC10985820
Cozma A., Sitar-Tăut A., Orășan O. et al. The Impact of Long COVID on the Quality of Life. Medicina 2024. Vol.60(8). P. 1-10 Doi.org/10.3390/medicina60081359
Dyer A., Böhnke J., Curran D., et al. A systematic review of quality of life and health-related quality of life as outcomes in substance and behavioural addictions. Wiley Online Library. 2023. P.1-21. DOI: 10.1111/dar.13717
Kim Y., Bae S., Chang H., et al. Long COVID prevalence and impact on quality of life 2 years after acute COVID-19. Scientific reportrs 13. 2023. Article number: 11207. Doi.org/10.1038/s41598-023-36995-4
Grishyna O., Menkus O. Problems of differential diagnosis of symptoms of post-traumatic stress disorder and Long COVID in wartime conditions in rheumatological patients. Collection of theses. 2024. P. 194-197 URL: file:///C:/Users/user/Downloads/tezy%20(1)%20(1).pdf
COVID-19. 2024 URL: https://www.cdc.gov/covid/long-term-effects/index.html
Meagher T. Long COVID - An Early Perspective. J Insur Med. 2021. Vol. 49 (1). P. 19–23. Doi.org/10.17849/insm-49-1-1-5.1
Krousel-Wood, M., Chambers, R., Muntner P. Clinicians' Guide to Statistics for Medical Practice and Research: Part I. Ochsner J. 2006 Winter; Vol. 6(2). P. 68–83. URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121570/
WHOQOL: Measuring Quality of Life. 2024. URL: https://www.who.int/tools/whoqol/whoqol-bref
Whoqol-Bref. Heartbeat. 2021.URL: https://heartbeat-med.com/resources/whoqol-bref/
Rashid U., Saeed Khan A., Dalal K., et al. Quality of life (QoL) among COVID-19 recovered healthcare workers in Bangladesh. BMC Health Serv Res. 2022. Article number: 716. DOI: 10.1186/s12913-022-07961-z
Тeschetna S. The ranking of countries by quality of life has been published: where is Ukraine? TV News Service. 2024. URL: https://tsn.ua/svit/opublikovano-reyting-krayin-za-yakistyu-zhittya-na-yakomu-misci-ukrayina-2659920.html
Sadova-Chuba Z., Slaba O., Hrushkovska D., et al. Is the quality of life of woman who went abroad during the full-scale Russian-Ukrainian war really higher compared to woman who stayed in Ukraine? Health and society. 2023. Vol.3 (97). P. 13-15. DOI: https://doi.org/10.11603/1681-2786.2023.3.14217]
Sadova-Chuba Z. T., Slaba O. R., Hurka O. I., et al. Factors affecting the quality of women's life in the conditions of the russian-ukrainian war. Bulletin of problems in biology and medicine. 2023. Issue 1. P. 360 – 366. DOI 10.29254/2077-4214-2023-1-168-360-366
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