Analysis of the current state of development of micro-needle systems for transdermal drug delivery (a scoping review)

Authors

DOI:

https://doi.org/10.15587/2519-4852.2026.352761

Keywords:

microneedle system, transdermal delivery, improved penetration of active substances, bibliosemantic analysis

Abstract

The aim is to examine the current state of development of microneedle systems for transdermal drug delivery.

Materials and methods. Analysis, systematization, and generalization of data from scientific literature sources on the development of microneedle systems, research on their effectiveness, and prospects for use in pharmacy. A modified Arskey O'Malley methodology was used, refined by a research group led by H.M. Daudt. A total of 480 publications from the last ten years were analysed.

Results. The results of the analysis show that most of the experimental studies focus on the development of microneedle systems for transdermal delivery of vaccines, insulin, and analgesics. In contrast, studies devoted to the creation of drugs with a different direction of action or drugs for the gradual release of active substances using microneedles occupy a smaller segment of the total number.

Conclusions. It has been established that most scientists choose to develop microneedle-based drugs for systemic use. The main areas of publication are reviews of literature sources, the development of new microneedle systems, etc. The results obtained indicate the potential and relevance of conducting research on the development of microneedle systems

Author Biographies

Liubov Bodnar, National University of Pharmacy

Assistant

Department of Drug Technology

Tetiana Kovalova, National University of Pharmacy

PhD, Associate Professor

Department of Drug Technology

Natalia Sydora, Private Higher Educational Establishment «Kyiv Medical University»

Doctor of Pharmaceutical Sciences, Professor

Department of Pharmaceutical and Biological Chemistry, Pharmacognosy

Oleksandr Shmalko, Petro Mohyla Black Sea National University

Doctor of Pharmaceutical Science, Associate Professor

Department of Pharmacy, Pharmacology, Medical, Bioorganic and Biological Chemistry

Medical Institute

Ihor Berdey, I. Horbachevsky Ternopil National Medical University

PhD, Associate Professor

Department of Pharmacy Management, Economics and Technology

Liliia Vyshnevska, National University of Pharmacy

Doctor of Pharmaceutical Science, Professor, Head of Department

Department of Drug Technology

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Analysis of the current state of development of micro-needle systems for transdermal drug delivery (a scoping review)

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2026-02-28

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Bodnar, L., Kovalova, T., Sydora, N., Shmalko, O., Berdey, I., & Vyshnevska, L. (2026). Analysis of the current state of development of micro-needle systems for transdermal drug delivery (a scoping review). ScienceRise: Pharmaceutical Science, (1 (59), 31–42. https://doi.org/10.15587/2519-4852.2026.352761

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No. 1 (59) (2026)

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Pharmaceutical Science

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Copyright (c) 2026 Liubov Bodnar, Tetiana Kovalova, Natalia Sydora, Oleksandr Shmalko, Ihor Berdey, Liliia Vyshnevska

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