Vector algebra theory in analysis of properties of antibacterial medications

N Boyko; A Zaytsev; T Osolodchenko

Автор(и)

N Boyko National University of Pharmacy,
A Zaytsev National University of Pharmacy,
T Osolodchenko Mechnikov Institute of Microbiology and Immunology,

Ключові слова:

vector algebra, antibacterial properties of medications

Анотація

The possibility to use vector algebra theory for quantitative description of antibacterial medications and comparison of their properties has been shown. Mathematic formulas for description of medications’ antibacterial
action basing on data of simple to use well method have been presented. This method allows evaluation of medications’ antibacterial activity and opportunity to choose the most active ones, as well as compare them with each other. It is noted that medications of natural origin are inferior to those of synthetic origin as for their antibacterial activity and new galenic medications possess the most antimicrobial properties. The prospects of this method for pharmacoeconomic analysis of medications conducted in order to chose optimal
cost/quality ratio has been demonstrated.

Посилання

Bailey N. Mathematics in medicine and biology. Translated from English by E.G. Kovalenko. - M.: "Mir". 1970. – 327 p.

Basic laboratory techniques in clinical bacteriology / Ed. WHO. - Geneva, 1994. – 131p.

Bashkova L.V. Analysis of the microflora of periodontal pockets in patients with rapidly progressive periodontitis / L.V. Bashkova, V.M Morgunov, E.E. Savin // Modern aspects of practical medicine: Proceedings of the Conference of interns and medical

residents. - Saratov, 2011. - P. 111-112.

Boyko N.N. Pharmacoeconomic analysis of antibacterial medications used in dentistry / N.N. Boyko, A.I. Zaytsev, L.V. Nefedova // Pharmacoeconomics in Ukraine: state and prospects of development: Proceedings of the Sixth Scientific

Conference. - Kharkov, 2013. - P..

Bronstein I.N. Handbook of mathematics for 26 engineers and students of technical colleges. 9th Edition / I.N. Bronstein, K.A. Semendyaev. - M., 1962. – 608 p.

Guidelines for susceptibility testing of microorganisms to antibacterial agents 4.2.1890-04 // Klin. microbiol. antimicrob.chimiother. № 4. – Vol. 6. – 2004. – P. 306-359.

Kochin N.E. Vector calculus and beginning of the

tensor calculus. 9th Edition. - Moscow: Nauka, 1965. –

p.

Osolodchenko T.P. Species of microflora of periodontatus / T.P. Osolodchenko, I.D. Baydalka, L.G. Shtiker, L.Y. Pushkar, S.V. Pilyugin // Annals of Mechnikov Institute. - № 3. – 2009. – P. 54-57.

Reshedko G.K. Determination of antibiotic sensitivity: methods, results, evaluation / G.K. Reshedko // Clinical Antimicrobial Chemotherapy, 1999. - N 3. - P.113-115.

State Pharmacopoeia of Ukraine / State Enterprise "Scientific and Expert Pharmacopoeias Centre." - 1st Ed. - H.: RIREH, 2001. - Appendix 1. - 2004. – 520 p.

State Pharmacopoeia of Ukraine / State Enterprise "Ukrainian Scientific Centre Pharmacopoeial quality of drugs." - 1st Ed. - Appendix 4. - Kharkov: State Enterprise "Ukrainian Scientific Centre Pharmacopoeial quality of drugs". - 2011. - 540 p.

Terekhina A.Y. Data analysis methods of multidimensional scaling. - Moscow: Nauka. Home Edition physical and mathematical literature, 1986. –168 p.

The study of the specific activity of antimicrobial drugs: a method. recommendations / Y. L. Volyanskiy, I. S. Gritsenko, V. P. Shyrokobokov et al. - K., 2004. - 38

p.

The study of the specific activity of antimicrobial drugs / Y. L. Volyanskiy, S. V. Biryukova, I. S. Gritsenko et al. - Kharkov, 2004. - 38 p.

Frich N.I. Analysis of antibiotic sensitivity of clinical strains, isolated in surgical and urologic hospitals of Ivano-Frankivsk / N.I. Frich // Annals of Mechnikov Institute. - № 2. – 2011. – P. 39-47.