Antibacterial activity of combination drugs for treating vaginosis different etiologies

L Bobritskaya; T Osolodchenko; E Ruban

Автор(и)

L Bobritskaya National University of Pharmacy,
T Osolodchenko Mechnikov Institute of Microbiology and Immunology,
E Ruban National University of Pharmacy,

Ключові слова:

antibacterials preparations, capsule, ornidazole, flamini, diclofenac sodium

Анотація

Investigated the antimicrobial activity of the combination preparation in capsules "Meraflam" clinical of microbial strains isolated from patients with bacterial vaginosis . Experimentally proved the therapeutic dose of 0.3 g ornidazole in combination with Flamini 0.05 g, improve tolerability and expand the range of antibacterial action of the drug. In view of the antimicrobial capacity of diclofenac sodium from the combination of ofloxacin proposed for use in an integrated circuit - inflammatory treatment of infectious diseases , including bacterial vaginosis.

Посилання

Tiberal in the treatment of bacterial vaginosis (pharmaceutical company F. Hoffmann-La Roche Ltd, Switzerland) . Information for health care professionals [Electronic resource]. - Access mode:

http://medi.ru./doc/2250102/htm

Current approaches to the treatment of trichomoniasis in women / V. K. Chaika, O.N. Rogovaia, G.M. Adamova [et al.] // Women’s doctor. - 2006. - № 2. - P. 9-15 .

Use of the "tiberal" in bacterial vaginosis. Information for health care professionals [Electronic resource]. - Access mode:

http://roche.com.ua/press_biblio_tiberal_07.shtml

Gomberg, M. A. Infection of the vagina: view of venereologist. Treatment of trichomoniasis and bacterial vaginosis: problems and solutions [Electronic resource] / M. A .Gomberg , K. Plahova // Consilium-Medicum. - 2005. - V.7, № 3. - Access mode:

http://media/consilium/05_03/210.shtml

Tikhomirov, A. L. Vulvovaginal candidiasis: a modern view of the problem / A.L. Tikhomirov, Ch.G. Oleinik // Farmatec. - 2003. - № 9. - P. 24 - 29.

Drug "Tiberal" in the treatment of bacterial vaginosis [Electronic resource] / V.N. Prilepskaya, A.S. Ancyra, V.V. Muraveva [et al.] // Gynecology. - 2006. - V. 8, № 4. - Access mode: www.consiliummedicum.com/article/7827

Characterization of vaginal microbial communities in adult healthy women using cultivation-independent methods / X. Zhou, SJ Bent S.J., M.G. Schneider [et al.] // Microbiology. - 2004. - V.150. - P. 2565-2573.

Clinical and cervical cytokine response to treatment with oral or vaginal metronidazole for bacterial vaginosis during pregnancy / M.H. Yudin, D.V. Landers, L. Meyn [et al.] // Obstet. & Gynecol. 2003 . -

V. 102, № 3. - P. 527-534.

Іvanyuta, S.O. Tiberal for fighting with resistance during trichomoniasis treatment in women [Electronic resource] / S.O. Іvanyuta // Women's Health. - 2005. - № 2. - Access mode::

http://roche.com.ua/press_biblio_tiberal_10.shtml

Ryzhko, P.P. The modern principles of integrated treatment of trichomonas and chlamydial infection / P.P. Ryzhko // Women's doctor. - 2008. - № 3. - P. 26 - 30.

Antibacterial properties of pharmaceutical compositions with ornidazole and flamini [Electronic resource] / Bobritskaya L.A., Ruban H.А., Osolodchenko T.P., Shcherbak O.N., Dmitrievskiy D.I.

// Annals of Mechnikov Institute. - 2013. - № 1. - P. 27 - 31. – Access mode: www.imiamn.org.ua / journal.htm

Fіlіmonova, N. І. Microbiological substantiation of effective combined use of glucocorticoids and nonsteroid anti-inflammatory drugs with antibiotics : Thesis for . Sciences : special. 03.00.07 "

microbiology" / N.І . Fіlіmonova. - Kharkiv, 2003. – 39

p.

The Order of USSR Ministry of Health, 22.04.1985 About unification of microbiological (bacteriological) research methods that are used in clinical diagnostic laboratories of medical institutions [Electronic resource]. - Access mode: zakon.law7.ru/legal2/se4/pravo4231/page12.htm

Bіryukova, S.V. The laboratory diagnostics of pyoinflammatory diseases caused by asporogenic anaerobic microorganisms : guideline / S.V. Bіryukova, Yu. L. Volyansky, I.Yu. Kuchma. - Kharkiv , 2000 . -

p.

Standardization of microbial suspension / Yu. L. Volyansky, L. G. Myronenko, S.V. Kalіnіchenko [ et al.] // Information letter about innovation in health care system, № 163. – 2006, Ministry of Health Ukraine ; Ukrainian center of scientific-medical information,

patent and license works (Ukrmedpatentіnform).