Method of organic carcinogenic substances control in different physical nature objects

Authors

DOI:

https://doi.org/10.15587/1729-4061.2014.26238

Keywords:

analytical control, chemical carcinogenesis, exogenous carcinogen, quantum dots, nanophotonics, polynuclear aromatic hydrocarbons

Abstract

Chemical carcinogenesis caused by intake of exogenous carcinogenic organic compounds is the most widespread reason for initiation and progress of cancer. So the analytical methods for such compounds detection should have low detection limits and high selectivity. Known analytical methods for the carcinogenic substances detection have a number of disadvantages and limitations. Therefore, we have proposed a new optical nanophotonic method for carcinogenic substances detection such as polynuclear aromatic hydrocarbons (PAH) in objects of different physical nature liquids in the first place. This method is based on main physical peculiarities of a new optical science called nanophotonics which, in short, describes size dependent optical transitions in quantum confined space. The article considers main principals of using nanophotonics for the purpose of chemical organic carcinogens detection with the help of so called nanophotonic analytical instruments – sensors. The latter main detection element constitutes nanophotonic material such as semiconductor quantum dots. The specific interactions of the organic carcinogens with the detection elements bringing to the emission of optical analytical signal represent the essence of nanophotonic analytical method revealing its advantages over known approaches. Proposed method and its instrumental realization for certain PAH detection was experimentally tested. As the detection elements semiconductor CdSe/ZnS/TOPO quantum dots were used. On the basis of the obtained results nanophotonic method of analytical control of exogenous carcinogenic substance was developed and its main characteristics were defined showing good perspective for its utilization in ecology, biomedicine and other fields. 

Author Biographies

Ольга Анатоліївна Сушко, Kharkiv National University of Radio Electronics 14, Lenin ave., Kharkiv, Ukraine, 61166

PhD student

Department of Biomedical Engineering

Микола Миколайович Рожицький, Department of Biomedical Engineering 14, Lenin ave., Kharkiv, Ukraine, 61166

Doctor of Physical and Mathematical Sciences, Professor

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Published

2014-08-08

How to Cite

Сушко, О. А., & Рожицький, М. М. (2014). Method of organic carcinogenic substances control in different physical nature objects. Eastern-European Journal of Enterprise Technologies, 4(6(70), 23–30. https://doi.org/10.15587/1729-4061.2014.26238

Issue

Vol. 4 No. 6(70) (2014): Technology organic and inorganic substances

Section

Technology organic and inorganic substances

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Copyright (c) 2014 Ольга Анатоліївна Сушко, Микола Миколайович Рожицький

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