Development of an approach to mathematical description of imbalance in methabolic processes for its application in the medical diagnostic information system

Authors

DOI:

https://doi.org/10.15587/1729-4061.2018.141451

Keywords:

flow cultivator, Lotka-Volterra model, metabolic syndrome, balance, approach, energy deposition, energy consumption

Abstract

The problem of diagnosing the metabolic syndrome associated with disturbance of carbohydrate and lipid metabolism was considered in this work. A new approach to determination of imbalance of metabolic processes was proposed. It is based on combining of the flow cultivator and the Lotka-Volterra models. Application of the model of flow cultivator provides an opportunity for objective assessment of initial conditions of behavior of the system acting as a human body and enables time matching of the model basic parameters. Initial conditions for modeling metabolic processes were determined using the Lotka-Volterra model. Use of these conditions makes it possible to determine stability of metabolic processes taking into account individual values of waist and hip circumference, weight, heart rate, age, systolic and diastolic pressure and the calculated Harris-Benedict value.

Cross-checking for a possible development of metabolic processes in people with normal and impaired metabolism has shown that the developed approach can be used in medical institutions for the early diagnosis of metabolic disorders. To establish balance of the metabolic processes that are characteristic of people without and with metabolic disorders, retrospective data of examination of 155 young people who were under observation for several years at Kharkiv municipal clinical hospital No. 11, Ukraine, have been analyzed.

The proposed approach is the basis of mathematical support of the medical diagnostic information system for detecting imbalance of metabolic processes which is developed currently. Application of such a system in the future will make it possible to study in detail the influence of various gender, territorial and age characteristics on the balance of metabolic processes in the human body.

Author Biographies

Hanna Dobrorodnia, Kharkiv National University of Radio Electronics Nauky ave., 14, Kharkiv, Ukraine, 61166

Postgraduate student

Department of biomedical engineering

Olena Vуsotska, Kharkiv National University of Radio Electronics Nauky ave., 14, Kharkiv, Ukraine, 61166

Doctor in Technical Sciences, Professor

Department of Information Control Systems

Marine Georgiyants, Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkіv, Ukraine, 61176

MD, Professor

Department of Pediatrics Anesthesiology and Intensive Therapy

Yurii Balym, Kharkiv State Zooveterinary Academy Academichna str., 1, Malaya Danylivka, Dergachi district, Kharkiv region, Ukraine, 62341

Doctor of Veterinary Sciences, Professor

Department of Reproductology

Larisa Rak, State Enterprise "Institute of Health Care of Children and Adolescents of the National Academy of Medical Sciences of Ukraine" Yuvileinyi ave., 52, Kharkiv, Ukraine, 61153

MD, Professor

Department of Pediatrics and Rehabilitation

Olena Kolesnikova, GI «L.T.Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine» 2-a, Avenue L. Malaya, Kharkiv, Ukraine, 61039

MD, PhD, Senior Researcher

Deputy director of scientific work

Victor Levykin, Kharkov National University of Radio Electronics Nauky ave., 14, Kharkiv, Ukraine, 61166

Doctor of Technical Sciences, Professor

Department of Department of Information Control Systems

Olexandr Dovnar, Kharkiv National University of Radio Electronics Nauky ave., 14, Kharkiv, Ukraine, 61166

PhD, Associate Professor

Department of Information Control Systems

Konstantin Nosov, V. N. Karazin Kharkiv National University Svobody sq., 4, Kharkiv, Ukraine, 61022

PhD

Scientific-research Department

Andrii Porvan, Kharkiv National University of Radio Electronics Nauky ave., 14, Kharkiv, Ukraine, 61166

PhD, Associate Professor

Department of Information Control Systems

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Published

2018-09-12

How to Cite

Dobrorodnia, H., Vуsotska O., Georgiyants, M., Balym, Y., Rak, L., Kolesnikova, O., Levykin, V., Dovnar, O., Nosov, K., & Porvan, A. (2018). Development of an approach to mathematical description of imbalance in methabolic processes for its application in the medical diagnostic information system. Eastern-European Journal of Enterprise Technologies, 5(2 (95), 29–39. https://doi.org/10.15587/1729-4061.2018.141451

Issue

Vol. 5 No. 2 (95) (2018): Information technology. Industry control systems

Section

Information technology

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Copyright (c) 2018 Hanna Dobrorodnia, Olena Vуsotska, Marine Georgiyants, Yurii Balym, Olexandr Dovnar, Larisa Rak, Konstantin Nosov, Andrii Porvan

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