Medical decisions under uncertainty

Authors

DOI:

https://doi.org/10.15587/1729-4061.2014.23935

Keywords:

decision-making, differential diagnosis, game theory, conjugate gradient method, linear programming

Abstract

The paper proposes a solution to the patients’ differential diagnosis problem by a combined application of the basic game theory, linear programming, and the conjugate gradient method. Based on the clinical research, a differential diagnosis of diseases such as atopic dermatitis, dermatitis herpetiformis, drug disease, psoriasis, eczema, scleroderma, lupus erythematosus, mycosis in 590 patients was carried out. Serum levels of T-lymphocytes, T-helper lymphocytes, cytotoxic T-cells; B-lymphocytes; s5 − interleukin 2; interleukin 6, endothelin-1 polypeptide; the percentage of segmented neutrophils in a leukogram; the serum IgA level; the serum IgM level; the serum immunoglobulin G level, s12 – the serum total immunoglobulin E level were considered informative features.

As a result of applying the proposed method not only the patient's diagnosis was determined, but also the doctor was given the opportunity to weigh the probability of possible medical diagnostic errors.

Using the approach, proposed by the authors to differentiate diagnoses with similar clinical implications, allows improving the efficiency of medical decision-making.

Author Biographies

Елена Владимировна Высоцкая, Kharkiv National University of Radioelectronics Lenina 14, Kharkov, Ukraine, 61166

Candidate of engineering science, Professor

Department of Biomedical Engineering

Александр Иосифович Довнарь, Kharkiv National University of Radio Electronics Lenina 14, Kharkov, Ukraine, 61166

PhD

Department of Biomedical Engineering

Анна Ивановна Печерская, Kharkiv National University of Radio Electronics Lenina 14, Kharkov, Ukraine, 61166

PhD

Department of Biomedical Engineering

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Published

2014-06-20

How to Cite

Высоцкая, Е. В., Довнарь, А. И., & Печерская, А. И. (2014). Medical decisions under uncertainty. Eastern-European Journal of Enterprise Technologies, 3(4(69), 16–20. https://doi.org/10.15587/1729-4061.2014.23935

Issue

Vol. 3 No. 4(69) (2014): Mathematics and Cybernetics - applied aspects

Section

Mathematics and Cybernetics - applied aspects

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Copyright (c) 2014 Елена Владимировна Высоцкая, Александр Иосифович Довнарь, Анна Ивановна Печерская

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