Predicting the course of atopic dermatitis in children using discrete simulation of dynamic systems

Authors

DOI:

https://doi.org/10.15587/1729-4061.2014.24878

Keywords:

predicting, atopic dermatitis, dynamic system, discrete simulation, Spearman's correlation matrices

Abstract

The authors propose an approach to predicting the course of atopic dermatitis (AD) using discrete simulation of dynamic systems (DSDS) based on the previously selected informative features, which allows to reveal hidden relationships between them and determine the nature of the AD course in children.For this, an array of observations is formed of prognostic factors, such as itch intensity, severity of the morphological elements of rash, prevalence of skin formations, ranked IgE index value. After that, the Spearman's correlation matrices between the parameters of the array of observations and rows of the minor of the dynamic system trajectory array are calculated.Then, the value of the function of distance between objects is minimized, the conditional-reference trajectory of the system for each parameter is built.Further, the system change pitch, which characterizes the patient's condition control points is found.Later, during individual examination of patients, their prognostic factors are recorded and compared with conventional-reference trajectory, defining the site, corresponding to the patient's condition at a certain time.The data-based trajectory allows to select a prognostic working hypothesis and determine the amount and mode of treatment for children with AD.

Author Biographies

Елена Владимировна Высоцкая, Kharkiv National University of Radioelectronics Lenina 14, Kharkov, Ukraine, 61166

Candidate of engineering science, Professor

Department of Biomedical Engineering

Андрей Павлович Порван, Kharkiv National University of Radioelektronik Lenina 16, Kharkov, Ukraine, 61166

Ph.D., Senior Researcher
Department of Biomedical Engineering

Юрий Гаврилович Беспалов, V. N. Karazin Kharkiv National University Svobody Sq. 4, 61022, Kharkiv, Ukraine

Senior Researcher
Laboratory Simulation of adaptive mechanisms

Константин Валентинович Носов, V. N. Karazin Kharkiv National University Svobody Sq. 4, 61022, Kharkiv, Ukraine

Ph.D., Researcher

Laboratory Simulation of adaptive mechanisms

Виктория Анатольевна Клименко, Kharkiv National Medical University Lenina 4, Kharkov, Ukraine, 61166

Professor, Doctor of Science

Chair of Propaedeutics pedіatrії number 2

Алексей Алексеевич Трубицын, Kharkiv National University of Radioelektronik Lenina 14, Kharkov, Ukraine, 61166

Engineer
Department of Design and operation of electronic devices

References

  1. Carroll, Cl., Balkrishnan, R., Feldman, S. (2005). The burden of atopic dermatitis: impact on the patient, family and society. Pediatric Dermatology, (22), 192–199.
  2. Kogan, B., Terletsky, V., Terletsky, R. (2005). Sovremennaya terapiya allergicheskikh dermatozov. Ukraїnsky zhurnal dermatologії venerologіi kosmetologії, (3(8)), 22–24.
  3. Karabutov, N. (2008). Strukturnaya identifikatsiya sistem. MGIU, 160.
  4. Bykh, A., Vysotskaya, E., Porvan, A., Klyuchnik, I., Trubitsyn, A. (2010). Metod analiza iyerarkhy pri postroyenii multifaktornykh modeley differentsialnoy diagnostiki atopicheskogo dermatita. Eastern-European Journal of enterprise tehnologies, Vol. 3, № 6 (45), 4–8.
  5. Vysotskaya, E., Bondarenko, T., Porvan, A., Bespalov, Yu., Nosov, K., Klimenko, V., Trubіtsin, O. (2013). Sposіb prognozuvannya perebіgu atopіchnogo dermatitu u dіtey. Patent Ukraїni na korisnu model №83397. Byul. (17).
  6. Vysotskaya, Ye., Pecherskaya, A., Soloshenko, E. (2013). Matematicheskoye modelirovaniye v differentsialnoy diagnostike lekarstvennoy bolezni. Zpravy vedecke ideje – 2013. Matematika. Moderni informachi technologie: Praha. Publishing House “Education and Science”, 27–30.
  7. Prangishvili, I., Lototsky, V., Ginsberg, K., Smolyaninov, V. (2004). Identifikatsiya sistem i zadachi upravleniya: na puti k sovremennym sistemnym setodologiyam. Problemy upravleniya, 4.
  8. Belan, E., Verovsky, V. (2006). Prognozirovaniye bronkhialnoy astmy u detey s atopicheskim dermatitom. Vestnik VolGMU.
  9. Vysotskaya, E., Belovol, A., Kirichenko, Yu. (2010). Formirovaniye vektora znachimykh pokazateley kliniko-biokhimicheskikh analizov patsiyentov s psoriazom s pomoshchyu iskusstvennoy neyronnoy seti dlya vyyavleniya zabolevaniya na rannikh stadiyakh. Prikladnaya radioelektronika, 9 (2), 280–284.
  10. Vysockaya, E., Kirichenko, U., Zukova, N. (2009). Obučenie iskusstvennoj nejronnoj seti dla diagnostirovaniâ dermatologicheskih zabolevanij pacientov. Sbornic dokladov II Vseukrainskoi nauchno-prakticheskoi konferencii «Informacionnye tehnologii i avtomatizacia», 20–21.
  11. Chikina, N., Antonova, I. (2007). Izuchenie vlijanija vnutrennih faktorov riska na razvitie allergodermatozov u rabochih himiko-farmacevticheskih predprijatij. Vestnik NTU «HPI» Tematicheskij vypusk: Informatika i modelirovanie, 19, 195–200.
  12. Chikina, N., Antonova, I. (2010). Nechetkaja ekspertnaja sistema prognoza riska razvitija professional’no obuslovlennyh zabolevanij. Vestnik NTU «HPI» Tematicheskij vypusk: Informatika i modelirovanie, 31, 127–132.
  13. Korablyov, N., Sorokina, I., Makogon, A. (2009). Differentsialnaya diagnostika allergodermatozov s ispolzovaniyem adaptivnoy modeli nechetkogo vyvoda. Sistemi obrobki іnformatsії, 3 (77).
  14. Bespalov, Yu., Derecha, L., Zholtkevich, G., Nosov, K. (2008). Diskretnaya model sistemy s otritsatelnymi obratnymi svyazyami. Vіsnik Kharkіvskogo natsіonalnogo unіversitetu Serіya «Matematichne modelyuvannya. Іnformatsіynі tekhnologії. Avtomatizovanі sistemi upravlіnnya», 833, 27–38.

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Published

2014-06-20

How to Cite

Высоцкая, Е. В., Порван, А. П., Беспалов, Ю. Г., Носов, К. В., Клименко, В. А., & Трубицын, А. А. (2014). Predicting the course of atopic dermatitis in children using discrete simulation of dynamic systems. Eastern-European Journal of Enterprise Technologies, 3(4(69), 21–25. https://doi.org/10.15587/1729-4061.2014.24878

Issue

Vol. 3 No. 4(69) (2014): Mathematics and Cybernetics - applied aspects

Section

Mathematics and Cybernetics - applied aspects

License

Copyright (c) 2014 Елена Владимировна Высоцкая, Андрей Павлович Порван, Юрий Гаврилович Беспалов, Константин Валентинович Носов, Виктория Анатольевна Клименко, Алексей Алексеевич Трубицын

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