Determining the medical and biological safety of meat-containing polycomponent products based on regional raw materials

Authors

DOI:

https://doi.org/10.15587/1729-4061.2022.268907

Keywords:

functional ingredients, meat-containing multicomponent products, dynamics of live weight, biochemical parameters of blood

Abstract

This paper reports medical and biological studies of semi­finished meat product and meat­containing semi­smoked sausage on laboratory rats. The purpose of the study was to investigate the effect of the developed products on the dynamics of live weight, the state of internal organs and tissues, general and biochemical parameters of the blood of animals when they are introduced into the standard diet in the amount of 30 %. The studies were conducted on 30 white nonlinear rats weighing 145–150 g, of which one control and two experimental groups were formed, according to the principle of the method of analog groups.
It is proved that the introduction of meat­containing multicomponent products with a high protein content into the diet of rats in the amount of 30 % of the standard diet contributes to the intensification of animal growth processes. It was confirmed that the increase in live body weight of rats after 21 days of the experiment amounted to 33–38 %, which is larger than that in control by 69–90 %.
No negative impact on the state of the internal organs of rats from the consumption of the developed products was detected.
It was found that the inclusion of meat­containing multicomponent products in the diet of rats contributes to an increase in erythropoiesis by 12.66 % compared to the starting data. The inclusion of products in the diet does not significantly change the content of leukocytes and platelets while increasing blood saturation with hemoglobin by 45.83–58.33 % higher compared to control animals.
The introduction into the diet of laboratory rats of meat­containing multicomponent products has an anabolic effect and contributes to an increase in the concentration of hemoglobin by 42.12 %, total protein by 4.79 %, creatinine by 19.68 %. In laboratory rats, there is a decrease in glucose by an average of 8.17 %, which indicates an intensification of processes in muscle tissue. Enhanced protein synthesis due to increased catabolism leads to an increase in bilirubin concentration by 19.12–21.97 % compared to control rats. Medical and biological studies of meat­containing multicomponent products can be applied in practice to confirm their safety

Author Biographies

Vasyl Pasichnyi, National University of Food Technologies

Doctor of Technical Sciences, Professor, Head of Department

Department of Technology of Meat and Meat Products

Vasyl Tischenko, Sumy National Agrarian University

PhD, Associate Professor

Department of Technology and Food Safety

Nataliia Bozhko, Medical Institute of Sumy State University

PhD, Associate Professor

Department of Biophysics, Biochemistry, Pharmacology and Biomolecular Engineering

Andrii Marynin, National University of Food Technologies

PhD, Associate Professor, Head of Laboratory

Problem Scientific and Research Laboratory

Oksana Moskaluyk, National University of Food Technologies

PhD, Senior Lecturer

Department of Technology of Meat and Meat Products

Alina Geredchuk, Poltava University of Economics and Trade

PhD, Senior Lecturer

Department of Food Industry Technologies and Restaurant Industry

References

  1. Dable-Tupas, G., Otero, M. C. B., Bernolo, L. (2020). Functional Foods and Health Benefits. Functional Foods and Nutraceuticals, 1–11. doi: https://doi.org/10.1007/978-3-030-42319-3_1
  2. Granato, D., Barba, F. J., Bursać Kovačević, D., Lorenzo, J. M., Cruz, A. G., Putnik, P. (2020). Functional Foods: Product Development, Technological Trends, Efficacy Testing, and Safety. Annual Review of Food Science and Technology, 11 (1), 93–118. doi: https://doi.org/10.1146/annurev-food-032519-051708
  3. John, R., Singla, A. (2021). Functional Foods: Components, health benefits, challenges, and major projects. DRC Sustainable Future: Journal of Environment, Agriculture, and Energy, 2 (1), 61–72. doi: https://doi.org/10.37281/drcsf/2.1.7
  4. Culhane, C. T. (2003). Functional foods–new perspectives. Journal of Nutraceuticals, Functional & Medical Foods, 4 (1), 67–77. doi: https://doi.org/10.1300/j133v04n01_07
  5. Santini, A. (2022). Nutraceuticals and Functional Foods: Is It Possible and Sustainable for Bridging Health and Food? Foods, 11 (11), 1608. doi: https://doi.org/10.3390/foods11111608
  6. Agostoni, C., Boccia, S., Banni, S., Mannucci, P. M., Astrup, A. (2021). Sustainable and personalized nutrition: From earth health to public health. European Journal of Internal Medicine, 86, 12–16. doi: https://doi.org/10.1016/j.ejim.2021.02.012
  7. Marcum, J. A. (2020). Nutrigenetics/Nutrigenomics, Personalized Nutrition, and Precision Healthcare. Current Nutrition Reports, 9 (4), 338–345. doi: https://doi.org/10.1007/s13668-020-00327-z
  8. Banerjee, P. (2019). Functional Food: A Brief Overview. International Journal of Bioresource Science, 6 (2). doi: https://doi.org/10.30954/2347-9655.02.2019.2
  9. Di Renzo, L., Gualtieri, P., Romano, L., Marrone, G., Noce, A., Pujia, A. et al. (2019). Role of Personalized Nutrition in Chronic-Degenerative Diseases. Nutrients, 11 (8), 1707. doi: https://doi.org/10.3390/nu11081707
  10. Bianchi, V. E., Herrera, P. F., Laura, R. (2019). Effect of nutrition on neurodegenerative diseases. A systematic review. Nutritional Neuroscience, 24 (10), 810–834. doi: https://doi.org/10.1080/1028415x.2019.1681088
  11. Lee, S. (2017). Strategic Design of Delivery Systems for Nutraceuticals. Nanotechnology Applications in Food, 65–86. doi: https://doi.org/10.1016/b978-0-12-811942-6.00004-2
  12. Sharma, M., Dwivedi, P., Singh Rawat, A. K., Dwivedi, A. K. (2016). Nutrition nutraceuticals: a proactive approach for healthcare. Nutraceuticals, 79–116. doi: https://doi.org/10.1016/b978-0-12-804305-9.00003-8
  13. Olmedilla-Alonso, B., Jiménez-Colmenero, F., Sánchez-Muniz, F. J. (2013). Development and assessment of healthy properties of meat and meat products designed as functional foods. Meat Science, 95 (4), 919–930. doi: https://doi.org/10.1016/j.meatsci.2013.03.030
  14. Gabdukaeva, L. Z., Gumerov, T. Y., Nurgalieva, A. R., Abdullina, L. V. (2021). Current trends in the development of functional meat products to improve the nutritional status of the population. IOP Conference Series: Earth and Environmental Science, 624 (1), 012196. doi: https://doi.org/10.1088/1755-1315/624/1/012196
  15. Strashynskiy, I., Fursik, O., Pasichniy, V., Marynin, A., Goncharov, G. (2016). Influence of functional food composition on the properties of meat mince systems. Eastern-European Journal of Enterprise Technologies, 6 (11 (84)), 53–58. doi: https://doi.org/10.15587/1729-4061.2016.86957
  16. Bozhko, N., Tischenko, V., Pasichnyi, V., Shubina, Y., Kyselov, O., Marynin, A., Strashynskyi, I. (2021). The quality characteristics of sausage prepared from different ratios of fish and duck meat. Potravinarstvo Slovak Journal of Food Sciences, 15, 26–32. doi: https://doi.org/10.5219/1482
  17. Bozhko, N., Tischenko, V., Pasichnyi, V., Matsuk, Y. (2020). Analysis of the possibility of fish and meat raw materials combination in products. Potravinarstvo Slovak Journal of Food Sciences, 14, 647–655. doi: https://doi.org/10.5219/1372
  18. House, J. D., Neufeld, J., Leson, G. (2010). Evaluating the Quality of Protein from Hemp Seed (Cannabis sativa L.) Products Through the use of the Protein Digestibility-Corrected Amino Acid Score Method. Journal of Agricultural and Food Chemistry, 58 (22), 11801–11807. doi: https://doi.org/10.1021/jf102636b
  19. Bozhko, N., Pasichnyi, V., Tischenko, V., Marynin, A., Shubina, Y., Strashynskyi, I. (2021). Determining the nutritional value and quality indicators of meat-containing bread made with hemp seeds flour (Cannabis sativa L.). Eastern-European Journal of Enterprise Technologies, 4 (11 (112)), 58–65. doi: https://doi.org/10.15587/1729-4061.2021.237806
  20. Pasichnyi, V., Bozhko, N., Tischenko, V., Marynin, A., Shubina, Y., Svyatnenko, R. et al. (2022). Studying the influence of berry extracts on the quality and safety indicators of half-smoked sausages. Eastern-European Journal of Enterprise Technologies, 1 (11 (115)), 33–40. doi: https://doi.org/10.15587/1729-4061.2022.252369
  21. Bozhko, N., Pasichnyi, V., Marynin, A., Tischenko, V., Strashynskyi, I., Kyselov, O. (2020). The efficiency of stabilizing the oxidative spoilage of meat-containing products with a balanced fat-acid composition. Eastern-European Journal of Enterprise Technologies, 3 (11 (105)), 38–45. doi: https://doi.org/10.15587/1729-4061.2020.205201
  22. European convention for the protection of vertebrate animals used for experimental and other scientific purposes (1986). Council of Europe. Strasbourg. URL: https://rm.coe.int/168007a67b
  23. Kozhemiakin, Yu. M., Khromov, O. S., Filonenko, M. A., Saifetdinova, H. A. (2002). Naukovo-praktychni rekomendatsii z utrymannia laboratornykh tvaryn ta roboty z nymy. Kyiv, 155.
  24. Mal'cev, A. I., Belousov, D. Yu. (2001). Eticheskaya otsenka metodik provedeniya issledovaniy. Ezhenedel'naya apteka, 4, 35.
  25. Kuwahara, S. S. (2012). Review of the Guide for the Care and Use of Laboratory Animals. Journal of GXP Compliance, 16 (1), 29–33.
  26. Song, S., Hua, C., Zhao, F., Li, M., Fu, Q., Hooiveld, G. J. E. J. et al. (2018). Purified Dietary Red and White Meat Proteins Show Beneficial Effects on Growth and Metabolism of Young Rats Compared to Casein and Soy Protein. Journal of Agricultural and Food Chemistry, 66 (38), 9942–9951. doi: https://doi.org/10.1021/acs.jafc.8b02521
  27. D’Aquila, P., De Rango, F., Paparazzo, E., Mandalà, M., Bellizzi, D., Passarino, G. (2022). Impact of Nutrition on Age-Related Epigenetic RNA Modifications in Rats. Nutrients, 14 (6), 1232. doi: https://doi.org/10.3390/nu14061232
  28. Guarasci, F., D’Aquila, P., Mandalà, M., Garasto, S., Lattanzio, F., Corsonello, A. et al. (2018). Aging and nutrition induce tissue-specific changes on global DNA methylation status in rats. Mechanisms of Ageing and Development, 174, 47–54. doi: https://doi.org/10.1016/j.mad.2018.02.001
  29. Hooda, J., Shah, A., Zhang, L. (2014). Heme, an Essential Nutrient from Dietary Proteins, Critically Impacts Diverse Physiological and Pathological Processes. Nutrients, 6 (3), 1080–1102. doi: https://doi.org/10.3390/nu6031080
  30. Kashani, K., Rosner, M. H., Ostermann, M. (2020). Creatinine: From physiology to clinical application. European Journal of Internal Medicine, 72, 9–14. doi: https://doi.org/10.1016/j.ejim.2019.10.025
  31. Brosnan, J. T., Brosnan, M. E. (2010). Creatine metabolism and the urea cycle. Molecular Genetics and Metabolism, 100, S49–S52. doi: https://doi.org/10.1016/j.ymgme.2010.02.020
  32. Sylow, L., Tokarz, V. L., Richter, E. A., Klip, A. (2021). The many actions of insulin in skeletal muscle, the paramount tissue determining glycemia. Cell Metabolism, 33 (4), 758–780. doi: https://doi.org/10.1016/j.cmet.2021.03.020
  33. Creeden, J. F., Gordon, D. M., Stec, D. E., Hinds, T. D. (2021). Bilirubin as a metabolic hormone: the physiological relevance of low levels. American Journal of Physiology-Endocrinology and Metabolism, 320 (2), E191–E207. doi: https://doi.org/10.1152/ajpendo.00405.2020
Determining the medical and biological safety of meat-containing polycomponent products based on regional raw materials

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Published

2022-12-30

How to Cite

Pasichnyi, V., Tischenko, V., Bozhko, N., Marynin, A., Moskaluyk, O., & Geredchuk, A. (2022). Determining the medical and biological safety of meat-containing polycomponent products based on regional raw materials. Eastern-European Journal of Enterprise Technologies, 6(11 (120), 126–133. https://doi.org/10.15587/1729-4061.2022.268907

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Section

Technology and Equipment of Food Production